RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3′-end extended forms of snRNAs

The Nuclear Exosome Targeting (NEXT) complex is a key cofactor of the mammalian nuclear exosome in the removal of Promoter Upstream Transcripts (PROMPTs) and potentially aberrant forms of other noncoding RNAs, such as snRNAs. NEXT is composed of three subunits SKIV2L2, ZCCHC8 and RBM7. We have recen...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hrossova, Dominika, Sikorsky, Tomas, Potesil, David, Bartosovic, Marek, Pasulka, Josef, Zdrahal, Zbynek, Stefl, Richard, Vanacova, Stepanka
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417160/
https://ncbi.nlm.nih.gov/pubmed/25852104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv240
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