Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture

Changes in mature microRNA (miRNA) levels that occur downstream of signaling cascades play an important role during human development and disease. However, the regulation of primary microRNA (pri-miRNA) genes remains to be dissected in detail. To address this, we followed a data-driven approach and...

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發表在:Nucleic Acids Res
Main Authors: Bouvy-Liivrand, Maria, Hernández de Sande, Ana, Pölönen, Petri, Mehtonen, Juha, Vuorenmaa, Tapio, Niskanen, Henri, Sinkkonen, Lasse, Kaikkonen, Minna Unelma, Heinäniemi, Merja
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
主題:
Computational Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737680/
https://ncbi.nlm.nih.gov/pubmed/28973462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx680
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