Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture

Changes in mature microRNA (miRNA) levels that occur downstream of signaling cascades play an important role during human development and disease. However, the regulation of primary microRNA (pri-miRNA) genes remains to be dissected in detail. To address this, we followed a data-driven approach and...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Bouvy-Liivrand, Maria, Hernández de Sande, Ana, Pölönen, Petri, Mehtonen, Juha, Vuorenmaa, Tapio, Niskanen, Henri, Sinkkonen, Lasse, Kaikkonen, Minna Unelma, Heinäniemi, Merja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Computational Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737680/
https://ncbi.nlm.nih.gov/pubmed/28973462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx680
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