The identification of FANCD2 DNA binding domains reveals nuclear localization sequences

Fanconi anemia (FA) is a recessive genetic disorder characterized by congenital abnormalities, progressive bone-marrow failure, and cancer susceptibility. The FA pathway consists of at least 21 FANC genes (FANCA-FANCV), and the encoded protein products interact in a common cellular pathway to gain r...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Niraj, Joshi, Caron, Marie-Christine, Drapeau, Karine, Bérubé, Stéphanie, Guitton-Sert, Laure, Coulombe, Yan, Couturier, Anthony M., Masson, Jean-Yves
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737651/
https://ncbi.nlm.nih.gov/pubmed/28666371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx543
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