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DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions
R-loops are three-stranded structures consisting of a DNA/RNA hybrid and a displaced DNA strand. The regulatory factors required to process this fundamental genetic structure near double-strand DNA breaks (DSBs) are not well understood. We previously reported that cellular depletion of the ATP-depen...
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| Опубликовано в: : | NAR Cancer |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520851/ https://ncbi.nlm.nih.gov/pubmed/33015627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa028 |
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