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Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress
Although oxidative stress has been shown to induce senescence and replication stress independently, no study has implicated unresolved replication stress as the driver for cellular senescence in response to oxidative stress. Using cells exposed to increasing concentrations of hydrogen peroxide, we s...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737622/ https://ncbi.nlm.nih.gov/pubmed/28985345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx684 |
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