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Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress
Although oxidative stress has been shown to induce senescence and replication stress independently, no study has implicated unresolved replication stress as the driver for cellular senescence in response to oxidative stress. Using cells exposed to increasing concentrations of hydrogen peroxide, we s...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737622/ https://ncbi.nlm.nih.gov/pubmed/28985345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx684 |
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