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Short inverted repeats contribute to localized mutability in human somatic cells

Selected repetitive sequences termed short inverted repeats (SIRs) have the propensity to form secondary DNA structures called hairpins. SIRs comprise palindromic arm sequences separated by short spacer sequences that form the hairpin stem and loop respectively. Here, we show that SIRs confer an inc...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zou, Xueqing, Morganella, Sandro, Glodzik, Dominik, Davies, Helen, Li, Yilin, Stratton, Michael R., Nik-Zainal, Serena
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737083/
https://ncbi.nlm.nih.gov/pubmed/28977645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx731
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