The genome as a record of environmental exposure

Whole genome sequencing of human tumours has revealed distinct patterns of mutation that hint at the causative origins of cancer. Experimental investigations of the mutations and mutation spectra induced by environmental mutagens have traditionally focused on single genes. With the advent of faster...

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Vydáno v:Mutagenesis
Hlavní autoři: Nik-Zainal, Serena, Kucab, Jill E., Morganella, Sandro, Glodzik, Dominik, Alexandrov, Ludmil B., Arlt, Volker M., Weninger, Annette, Hollstein, Monica, Stratton, Michael R., Phillips, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Special Topic: Exposomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637815/
https://ncbi.nlm.nih.gov/pubmed/26443852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev073
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