The genome as a record of environmental exposure

Whole genome sequencing of human tumours has revealed distinct patterns of mutation that hint at the causative origins of cancer. Experimental investigations of the mutations and mutation spectra induced by environmental mutagens have traditionally focused on single genes. With the advent of faster...

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Veröffentlicht in:Mutagenesis
Hauptverfasser: Nik-Zainal, Serena, Kucab, Jill E., Morganella, Sandro, Glodzik, Dominik, Alexandrov, Ludmil B., Arlt, Volker M., Weninger, Annette, Hollstein, Monica, Stratton, Michael R., Phillips, David H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Special Topic: Exposomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637815/
https://ncbi.nlm.nih.gov/pubmed/26443852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev073
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