Native or Proteolytically Activated NanI Sialidase Enhances the Binding and Cytotoxic Activity of Clostridium perfringens Enterotoxin and Beta Toxin

Many Clostridium perfringens strains produce NanI as their major sialidase. Previous studies showed that NanI could potentiate C. perfringens epsilon toxin cytotoxicity by enhancing the binding of this toxin to host cells. The present study first determined that NanI exerts similar cytotoxicity-enha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Theoret, James R., Li, Jihong, Navarro, Mauricio A., Garcia, Jorge P., Uzal, Francisco A., McClane, Bruce A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Molecular Pathogenesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736825/
https://ncbi.nlm.nih.gov/pubmed/29038129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00730-17
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