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Transcriptomic analysis of mitochondrial TFAM depletion changing cell morphology and proliferation
Human mitochondrial transcription factor A (TFAM) has been implicated in promoting tumor growth and invasion. TFAM activates mitochondrial DNA (mtDNA) transcription, and affects nuclear gene expression through mitochondrial retrograde signaling. In this study, we investigated the effects of TFAM dep...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736646/ https://ncbi.nlm.nih.gov/pubmed/29259235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18064-9 |
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