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Transcriptomic analysis of mitochondrial TFAM depletion changing cell morphology and proliferation

Human mitochondrial transcription factor A (TFAM) has been implicated in promoting tumor growth and invasion. TFAM activates mitochondrial DNA (mtDNA) transcription, and affects nuclear gene expression through mitochondrial retrograde signaling. In this study, we investigated the effects of TFAM dep...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lee, Woo Rin, Na, Heeju, Lee, Seon Woo, Lim, Won-Jun, Kim, Namshin, Lee, J. Eugene, Kang, Changwon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736646/
https://ncbi.nlm.nih.gov/pubmed/29259235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18064-9
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