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The mitochondrial transcription factor TFAM in neurodegeneration: Emerging evidence and mechanisms

The mitochondrial transcription factor A, or TFAM, is a mitochondrial DNA (mtDNA) binding protein essential for genome maintenance. TFAM functions in determining the abundance of the mitochondrial genome by regulating packaging, stability, and replication. More recently, TFAM has been shown to play...

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Detalles Bibliográficos
Publicado en:FEBS Lett
Autores principales: Kang, Inhae, Chu, Charleen T., Kaufman, Brett A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851836/
https://ncbi.nlm.nih.gov/pubmed/29364506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12989
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