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The mitochondrial transcription factor TFAM in neurodegeneration: Emerging evidence and mechanisms

The mitochondrial transcription factor A, or TFAM, is a mitochondrial DNA (mtDNA) binding protein essential for genome maintenance. TFAM functions in determining the abundance of the mitochondrial genome by regulating packaging, stability, and replication. More recently, TFAM has been shown to play...

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Detalles Bibliográficos
Publicado en:FEBS Lett
Main Authors: Kang, Inhae, Chu, Charleen T., Kaufman, Brett A.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851836/
https://ncbi.nlm.nih.gov/pubmed/29364506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12989
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