HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

Understanding how broadly neutralizing antibodies (bnAbs) to HIV envelope (Env) develop during natural infection can help guide the rational design of an HIV vaccine. Here, we described a bnAb lineage targeting the Env V2 apex and the Ab-Env co-evolution that led to development of neutralization bre...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Landais, Elise, Murrell, Ben, Briney, Bryan, Murrell, Sasha, Rantalainen, Kimmo, Berndsen, Zachary T., Ramos, Alejandra, Wickramasinghe, Lalinda, Smith, Melissa Laird, Eren, Kemal, de Val, Natalia, Wu, Mengyu, Cappelletti, Audrey, Umotoy, Jeffrey, Lie, Yolanda, Wrin, Terri, Algate, Paul, Chan-Hui, Po-Ying, Karita, Etienne, Ward, Andrew B., Wilson, Ian A., Burton, Dennis R., Smith, Davey, Kosakovsky Pond, Sergei L., Poignard, Pascal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736302/
https://ncbi.nlm.nih.gov/pubmed/29166592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.11.002
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