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A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats
Neuroinflammation is potentiated by early degeneration of the locus coeruleus noradrenergic pathway (LC-NE) commonly seen in aging-related neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. In animal models, lipopolysaccharide (LPS) induces strong peripheral immune respo...
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| Yayımlandı: | PLoS One |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736222/ https://ncbi.nlm.nih.gov/pubmed/29261743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189821 |
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