Murine Model of Progressive Orthopedic Wear Particle-Induced Chronic Inflammation and Osteolysis

Periprosthetic osteolysis and subsequent aseptic loosening of total joint replacements are driven by byproducts of wear released from the implant. Wear particles cause macrophage-mediated inflammation that culminates with periprosthetic bone loss. Most current animal models of particle-induced osteo...

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Bibliografiske detaljer
Udgivet i:Tissue Eng Part C Methods
Main Authors: Pajarinen, Jukka, Nabeshima, Akira, Lin, Tzu-hua, Sato, Taishi, Gibon, Emmanuel, Jämsen, Eemeli, Lu, Laura, Nathan, Karthik, Yao, Zhenyu, Goodman, Stuart B.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2017
Fag:
Special Focus Articles*
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734159/
https://ncbi.nlm.nih.gov/pubmed/28978284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2017.0166
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