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Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

OBJECTIVE: Severe hepatic ischemia reperfusion injury (IRI) can result in poor short- and long-term graft outcome after transplantation. The way to improve the viability of livers from donors after circulatory death (DCD) is currently limited. The aim of the present study was to explore the protecti...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Liu, Zhongzhong, Zhang, Xingjian, Xiao, Qi, Ye, Shaojun, Lai, Chin-Hui, Luo, Jun, Huang, Xiaoying, Wang, Wei, Zeng, Cheng, Zhong, Zibiao, Fan, Xiaoli, Xia, Zhiping, Xiong, Yan, Mao, Xinfang, Ye, Qifa, Wang, Yanfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733890/
https://ncbi.nlm.nih.gov/pubmed/29348789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3861914
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