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Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway

Mild hypothermia is known to protect against ischemia and reperfusion (IR) injury. The exact mechanisms of the protection are not fully understood. Forkhead box O3 (FOXO3a) has been defined as a critical mediator in cellular processes, including oxidative stress, apoptosis, inflammation, cell death...

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Publicat a:Mol Med Rep
Autors principals: Xiao, Qi, Ye, Qifa, Wang, Wei, Xiao, Jiansheng, Fu, Biqi, Xia, Zhiping, Zhang, Xingjian, Liu, Zhongzhong, Zeng, Xianpeng
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865885/
https://ncbi.nlm.nih.gov/pubmed/28944825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7501
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