Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway

Mild hypothermia is known to protect against ischemia and reperfusion (IR) injury. The exact mechanisms of the protection are not fully understood. Forkhead box O3 (FOXO3a) has been defined as a critical mediator in cellular processes, including oxidative stress, apoptosis, inflammation, cell death...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Xiao, Qi, Ye, Qifa, Wang, Wei, Xiao, Jiansheng, Fu, Biqi, Xia, Zhiping, Zhang, Xingjian, Liu, Zhongzhong, Zeng, Xianpeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865885/
https://ncbi.nlm.nih.gov/pubmed/28944825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7501
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