Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

OBJECTIVE: Severe hepatic ischemia reperfusion injury (IRI) can result in poor short- and long-term graft outcome after transplantation. The way to improve the viability of livers from donors after circulatory death (DCD) is currently limited. The aim of the present study was to explore the protecti...

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Udgivet i:Oxid Med Cell Longev
Main Authors: Liu, Zhongzhong, Zhang, Xingjian, Xiao, Qi, Ye, Shaojun, Lai, Chin-Hui, Luo, Jun, Huang, Xiaoying, Wang, Wei, Zeng, Cheng, Zhong, Zibiao, Fan, Xiaoli, Xia, Zhiping, Xiong, Yan, Mao, Xinfang, Ye, Qifa, Wang, Yanfeng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733890/
https://ncbi.nlm.nih.gov/pubmed/29348789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3861914
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