Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury

Ischemia-reperfusion injury (IRI) is an inevitable and serious clinical problem in donations after heart death (DCD) liver transplantation. Excessive sterile inflammation plays a fateful role in liver IRI. Hypothermic oxygenated perfusion (HOPE), as an emerging organ preservation technology, has a b...

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Vydáno v:Cell Death Dis
Hlavní autoři: Zhou, Wei, Zhong, Zibiao, Lin, Danni, Liu, Zhongzhong, Zhang, Qiuyan, Xia, Haoyang, Peng, Sheng, Liu, Anxiong, Lu, Zhongshan, Wang, Yanfeng, Ye, Shaojun, Ye, Qifa
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904838/
https://ncbi.nlm.nih.gov/pubmed/33627626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03493-2
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