GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition

Objective: Idiopathic pulmonary fibrosis is an irreversible and progressive fibrotic lung disease that leads to declines in pulmonary function and, eventually, respiratory failure and has no effective treatment. Gly-His-Lys (GHK) is a tripeptide involved in the processes of tissue regeneration and w...

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Publicat a:Front Pharmacol
Autors principals: Zhou, Xiao-Ming, Wang, Gui-Liang, Wang, Xiao-Bo, Liu, Li, Zhang, Qin, Yin, Yan, Wang, Qiu-Yue, Kang, Jian, Hou, Gang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733019/
https://ncbi.nlm.nih.gov/pubmed/29311918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00904
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