Induced Pluripotent Stem Cells Inhibit Bleomycin-Induced Pulmonary Fibrosis in Mice through Suppressing TGF-β1/Smad-Mediated Epithelial to Mesenchymal Transition

Pulmonary fibrosis is a progressive and irreversible fibrotic lung disorder with high mortality and few treatment options. Recently, induced pluripotent stem (iPS) cells have been considered as an ideal resource for stem cell-based therapy. Although, an earlier study demonstrated the therapeutic eff...

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Udgivet i:Front Pharmacol
Main Authors: Zhou, Yan, He, Zhong, Gao, Yuan, Zheng, Rui, Zhang, Xiaoye, Zhao, Li, Tan, Mingqi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108931/
https://ncbi.nlm.nih.gov/pubmed/27895584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00430
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