Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition

BACKGROUND: Our earlier report indicated that active vitamin D3 inhibited epithelial-mesenchymal transition (EMT) in bleomycin (BLM)-induced pulmonary fibrosis. The objective of this study was to further investigate whether vitamin D deficiency exacerbates BLM-induced pulmonary fibrosis. METHODS: Th...

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Foilsithe in:Respir Res
Main Authors: Li, Se-Ruo, Tan, Zhu-Xia, Chen, Yuan-Hua, Hu, Biao, Zhang, Cheng, Wang, Hua, Zhao, Hui, Xu, De-Xiang
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882226/
https://ncbi.nlm.nih.gov/pubmed/31775746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1232-6
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