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Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice

AIMS: The intraportal pancreatic islet transplantation (IPIT) model of diabetic rats is an insulin mediated model of hepatocarcinogenesis characterized by the induction of clear cell foci (CCF) of altered hepatocytes, which are pre-neoplastic lesions excessively storing glycogen (glycogenosis) and e...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Ribback, Silvia, Sonke, Jenny, Lohr, Andrea, Frohme, Josephine, Peters, Kristin, Holm, Johannes, Peters, Michele, Cigliano, Antonio, Calvisi, Diego F., Dombrowski, Frank
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732809/
https://ncbi.nlm.nih.gov/pubmed/29262643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22234
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