Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice

AIMS: The intraportal pancreatic islet transplantation (IPIT) model of diabetic rats is an insulin mediated model of hepatocarcinogenesis characterized by the induction of clear cell foci (CCF) of altered hepatocytes, which are pre-neoplastic lesions excessively storing glycogen (glycogenosis) and e...

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Vydáno v:Oncotarget
Hlavní autoři: Ribback, Silvia, Sonke, Jenny, Lohr, Andrea, Frohme, Josephine, Peters, Kristin, Holm, Johannes, Peters, Michele, Cigliano, Antonio, Calvisi, Diego F., Dombrowski, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732809/
https://ncbi.nlm.nih.gov/pubmed/29262643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22234
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