Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice

AIMS: The intraportal pancreatic islet transplantation (IPIT) model of diabetic rats is an insulin mediated model of hepatocarcinogenesis characterized by the induction of clear cell foci (CCF) of altered hepatocytes, which are pre-neoplastic lesions excessively storing glycogen (glycogenosis) and e...

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Udgivet i:Oncotarget
Main Authors: Ribback, Silvia, Sonke, Jenny, Lohr, Andrea, Frohme, Josephine, Peters, Kristin, Holm, Johannes, Peters, Michele, Cigliano, Antonio, Calvisi, Diego F., Dombrowski, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732809/
https://ncbi.nlm.nih.gov/pubmed/29262643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22234
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