Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism

Clear cell foci (CCF) of the liver are considered to be pre-neoplastic lesions of hepatocellular adenomas and carcinomas. They are hallmarked by glycogen overload and activation of AKT (v-akt murine thymoma viral oncogene homolog)/mTOR (mammalian target of rapamycin)-signaling. Here, we report the t...

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Udgivet i:Molecules
Main Authors: Metzendorf, Christoph, Wineberger, Katharina, Rausch, Jenny, Cigliano, Antonio, Peters, Kristin, Sun, Baodong, Mennerich, Daniela, Kietzmann, Thomas, Calvisi, Diego F., Dombrowski, Frank, Ribback, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570661/
https://ncbi.nlm.nih.gov/pubmed/32927708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184141
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