Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice

AIMS: The intraportal pancreatic islet transplantation (IPIT) model of diabetic rats is an insulin mediated model of hepatocarcinogenesis characterized by the induction of clear cell foci (CCF) of altered hepatocytes, which are pre-neoplastic lesions excessively storing glycogen (glycogenosis) and e...

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發表在:Oncotarget
Main Authors: Ribback, Silvia, Sonke, Jenny, Lohr, Andrea, Frohme, Josephine, Peters, Kristin, Holm, Johannes, Peters, Michele, Cigliano, Antonio, Calvisi, Diego F., Dombrowski, Frank
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732809/
https://ncbi.nlm.nih.gov/pubmed/29262643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22234
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