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Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines

Increasing evidence points to a key role played by epithelial-mesenchymal transition (EMT) in cancer progression and drug resistance. In this study, we used wet and in silico approaches to investigate whether EMT phenotypes are associated to resistance to target therapy in a non-small cell lung canc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fustaino, Valentina, Presutti, Dario, Colombo, Teresa, Cardinali, Beatrice, Papoff, Giuliana, Brandi, Rossella, Bertolazzi, Paola, Felici, Giovanni, Ruberti, Giovina
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732732/
https://ncbi.nlm.nih.gov/pubmed/29262566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21132
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