Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model

Medulloblastoma (MB), the tumor of the cerebellum, is the most frequent brain cancer in childhood and a major cause of pediatric mortality. Based on gene profiling, four MB subgroups have been identified, i.e., Wnt or Sonic Hedgehog (Shh) types, and subgroup 3 or 4. The Shh-type MB has been shown to...

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Veröffentlicht in:PLoS One
Hauptverfasser: Presutti, Dario, Ceccarelli, Manuela, Micheli, Laura, Papoff, Giuliana, Santini, Simonetta, Samperna, Simone, Lalli, Cristiana, Zentilin, Lorena, Ruberti, Giovina, Tirone, Felice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851620/
https://ncbi.nlm.nih.gov/pubmed/29538458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194206
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