Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni

著者: Lalli, Cristiana, Guidi, Alessandra, Gennari, Nadia, Altamura, Sergio, Bresciani, Alberto, Ruberti, Giovina
出版年 PLoS Negl Trop Dis (2015)

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive System...

著者: Guidi, Alessandra, Lalli, Cristiana, Perlas, Emerald, Bolasco, Giulia, Nibbio, Martina, Monteagudo, Edith, Bresciani, Alberto, Ruberti, Giovina
出版年 PLoS Negl Trop Dis (2016)

N-Terminal and C-Terminal Domains of Calmodulin Mediate FADD and TRADD Interaction

著者: Papoff, Giuliana, Trivieri, Nadia, Marsilio, Sonia, Crielesi, Roberta, Lalli, Cristiana, Castellani, Loriana, Balog, Edward M., Ruberti, Giovina
出版年 PLoS One (2015)

Chemical Investigation of the Indonesian Tunicate Polycarpa aurata and Evaluation of the Effects Against Schistosoma mansoni of the Novel Alkaloids Polyaurines A and B

著者: Casertano, Marcello, Imperatore, Concetta, Luciano, Paolo, Aiello, Anna, Putra, Masteria Yunovilsa, Gimmelli, Roberto, Ruberti, Giovina, Menna, Marialuisa
出版年 Mar Drugs (2019)

MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells

著者: Presutti, Dario, Santini, Simonetta, Cardinali, Beatrice, Papoff, Giuliana, Lalli, Cristiana, Samperna, Simone, Fustaino, Valentina, Giannini, Giuseppe, Ruberti, Giovina
出版年 PLoS One (2015)

Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines

著者: Fustaino, Valentina, Presutti, Dario, Colombo, Teresa, Cardinali, Beatrice, Papoff, Giuliana, Brandi, Rossella, Bertolazzi, Paola, Felici, Giovanni, Ruberti, Giovina
出版年 Oncotarget (2017)

CASP4 gene silencing in epithelial cancer cells leads to impairment of cell migration, cell-matrix adhesion and tissue invasion

著者: Papoff, Giuliana, Presutti, Dario, Lalli, Cristiana, Bolasco, Giulia, Santini, Simonetta, Manelfi, Candida, Fustaino, Valentina, Alemà, Stefano, Ruberti, Giovina
出版年 Sci Rep (2018)

Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production

著者: Guidi, Alessandra, Lalli, Cristiana, Gimmelli, Roberto, Nizi, Emanuela, Andreini, Matteo, Gennari, Nadia, Saccoccia, Fulvio, Harper, Steven, Bresciani, Alberto, Ruberti, Giovina
出版年 PLoS Negl Trop Dis (2017)

Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model

著者: Presutti, Dario, Ceccarelli, Manuela, Micheli, Laura, Papoff, Giuliana, Santini, Simonetta, Samperna, Simone, Lalli, Cristiana, Zentilin, Lorena, Ruberti, Giovina, Tirone, Felice
出版年 PLoS One (2018)

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

著者: Guidi, Alessandra, Saccoccia, Fulvio, Gennari, Nadia, Gimmelli, Roberto, Nizi, Emanuela, Lalli, Cristiana, Paonessa, Giacomo, Papoff, Giuliana, Bresciani, Alberto, Ruberti, Giovina
出版年 Parasit Vectors (2018)

Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by (1)H-NMR spectroscopy

著者: Guidi, Alessandra, Petrella, Greta, Fustaino, Valentina, Saccoccia, Fulvio, Lentini, Sara, Gimmelli, Roberto, Di Pietro, Giulia, Bresciani, Alberto, Cicero, Daniel Oscar, Ruberti, Giovina
出版年 PLoS Negl Trop Dis (2020)

Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced Form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone

著者: Imperatore, Concetta, Gimmelli, Roberto, Persico, Marco, Casertano, Marcello, Guidi, Alessandra, Saccoccia, Fulvio, Ruberti, Giovina, Luciano, Paolo, Aiello, Anna, Parapini, Silvia, Avunduk, Sibel, Basilico, Nicoletta, Fattorusso, Caterina, Menna, Marialuisa
出版年 Mar Drugs (2020)

ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis

著者: Compagnone, Mirco, Gatti, Veronica, Presutti, Dario, Ruberti, Giovina, Fierro, Claudia, Markert, Elke Katrin, Vousden, Karen H., Zhou, Huiqing, Mauriello, Alessandro, Anemone, Lucia, Bongiorno-Borbone, Lucilla, Melino, Gerry, Peschiaroli, Angelo
出版年 Proc Natl Acad Sci U S A (2017)

Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation

著者: Saraswati, A. Prasanth, Relitti, Nicola, Brindisi, Margherita, Osko, Jeremy D., Chemi, Giulia, Federico, Stefano, Grillo, Alessandro, Brogi, Simone, McCabe, Niamh H., Turkington, Richard C., Ibrahim, Ola, O’Sullivan, Jeffrey, Lamponi, Stefania, Ghanim, Magda, Kelly, Vincent P., Zisterer, Daniela, Amet, Rebecca, Hannon Barroeta, Patricia, Vanni, Francesca, Ulivieri, Cristina, Herp, Daniel, Sarno, Federica, Di Costanzo, Antonella, Saccoccia, Fulvio, Ruberti, Giovina, Jung, Manfred, Altucci, Lucia, Gemma, Sandra, Butini, Stefania, Christianson, David W., Campiani, Giuseppe
出版年 ACS Med Chem Lett (2020)

Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors

著者: Campiani, Giuseppe, Cavella, Caterina, Osko, Jeremy D., Brindisi, Margherita, Relitti, Nicola, Brogi, Simone, Saraswati, A. Prasanth, Federico, Stefano, Chemi, Giulia, Maramai, Samuele, Carullo, Gabriele, Jaeger, Benedikt, Carleo, Alfonso, Benedetti, Rosaria, Sarno, Federica, Lamponi, Stefania, Rottoli, Paola, Bargagli, Elena, Bertucci, Carlo, Tedesco, Daniele, Herp, Daniel, Senger, Johanna, Ruberti, Giovina, Saccoccia, Fulvio, Saponara, Simona, Gorelli, Beatrice, Valoti, Massimo, Kennedy, Breándan, Sundaramurthi, Husvinee, Butini, Stefania, Jung, Manfred, Roach, Katy M., Altucci, Lucia, Bradding, Peter, Christianson, David W., Gemma, Sandra, Prasse, Antje
出版年 J Med Chem (2021)