Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines

Increasing evidence points to a key role played by epithelial-mesenchymal transition (EMT) in cancer progression and drug resistance. In this study, we used wet and in silico approaches to investigate whether EMT phenotypes are associated to resistance to target therapy in a non-small cell lung canc...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Fustaino, Valentina, Presutti, Dario, Colombo, Teresa, Cardinali, Beatrice, Papoff, Giuliana, Brandi, Rossella, Bertolazzi, Paola, Felici, Giovanni, Ruberti, Giovina
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732732/
https://ncbi.nlm.nih.gov/pubmed/29262566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21132
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