Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

Heterozygous mutations in the NLRP3 gene in patients with cryopyrin associated periodic syndrome (CAPS) lead to hyper-responsive inflammasome function. CAPS is a systemic auto-inflammatory syndrome characterized by the activation of the innate immune system induced by elevated pro-inflammatory cytok...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Johnson, Jennifer L., Ramadass, Mahalakshmi, Haimovich, Ariela, McGeough, Matthew D., Zhang, Jinzhong, Hoffman, Hal M., Catz, Sergio D.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732154/
https://ncbi.nlm.nih.gov/pubmed/29322034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00507
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker