Neutrophil azurophilic granule exocytosis is primed by TNF-α and partially regulated by NADPH oxidase

Neutrophil (polymorphonuclear leukocyte) activation with release of granule contents plays an important role in the pathogenesis of acute lung injury, prompting clinical trials of inhibitors of neutrophil elastase. Despite mounting evidence for neutrophil-mediated host tissue damage in a variety of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Innate Immun
Prif Awduron: Potera, Renee M, Jensen, Melissa J, Hilkin, Brieanna M, South, Gina K, Hook, Jessica S, Gross, Emily A, Moreland, Jessica G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805152/
https://ncbi.nlm.nih.gov/pubmed/27655046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425916668980
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