Neutrophil azurophilic granule exocytosis is primed by TNF-α and partially regulated by NADPH oxidase

Neutrophil (polymorphonuclear leukocyte) activation with release of granule contents plays an important role in the pathogenesis of acute lung injury, prompting clinical trials of inhibitors of neutrophil elastase. Despite mounting evidence for neutrophil-mediated host tissue damage in a variety of...

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Udgivet i:Innate Immun
Main Authors: Potera, Renee M, Jensen, Melissa J, Hilkin, Brieanna M, South, Gina K, Hook, Jessica S, Gross, Emily A, Moreland, Jessica G
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805152/
https://ncbi.nlm.nih.gov/pubmed/27655046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425916668980
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