Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis

Mutations in DNA repair pathways are frequent in human cancers. Hence, gaining insights into the interaction of DNA repair genes is key to development of novel tumor-specific treatment strategies. In this study, we tested the functional relationship in development and oncogenesis between the homolog...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tanori, Mirella, Casciati, Arianna, Berardinelli, Francesco, Leonardi, Simona, Pasquali, Emanuela, Antonelli, Francesca, Tanno, Barbara, Giardullo, Paola, Pannicelli, Alessandro, Babini, Gabriele, De Stefano, Ilaria, Sgura, Antonella, Mancuso, Mariateresa, Saran, Anna, Pazzaglia, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731848/
https://ncbi.nlm.nih.gov/pubmed/29254138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10479
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