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Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection

The non-pathogenic parvovirus, adeno-associated virus (AAV), is an efficient vector for transgene expression in vivo and shows promise for treatment of brain disorders in clinical trials. Currently, there are more than 100 AAV serotypes identified that differ in the binding capacity of capsid protei...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hammond, Sean L., Leek, Ashley N., Richman, Evan H., Tjalkens, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731760/
https://ncbi.nlm.nih.gov/pubmed/29244806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188830
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