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Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection

The non-pathogenic parvovirus, adeno-associated virus (AAV), is an efficient vector for transgene expression in vivo and shows promise for treatment of brain disorders in clinical trials. Currently, there are more than 100 AAV serotypes identified that differ in the binding capacity of capsid protei...

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Vydáno v:PLoS One
Hlavní autoři: Hammond, Sean L., Leek, Ashley N., Richman, Evan H., Tjalkens, Ronald B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731760/
https://ncbi.nlm.nih.gov/pubmed/29244806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188830
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