Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats

Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased renal blood flow (RBF) and glomerular filtration. The aim of this study was to...

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Publicado en:Braz J Med Biol Res
Autores principales: Caires, A., Fernandes, G.S., Leme, A.M., Castino, B., Pessoa, E.A., Fernandes, S.M., Fonseca, C.D., Vattimo, M.F., Schor, N., Borges, F.T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Associação Brasileira de Divulgação Científica 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731326/
https://ncbi.nlm.nih.gov/pubmed/29267497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20176373
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