Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats

Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased renal blood flow (RBF) and glomerular filtration. The aim of this study was to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Braz J Med Biol Res
Main Authors: Caires, A., Fernandes, G.S., Leme, A.M., Castino, B., Pessoa, E.A., Fernandes, S.M., Fonseca, C.D., Vattimo, M.F., Schor, N., Borges, F.T.
Format: Artigo
Jezik:Inglês
Izdano: Associação Brasileira de Divulgação Científica 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731326/
https://ncbi.nlm.nih.gov/pubmed/29267497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20176373
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