Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats

Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased renal blood flow (RBF) and glomerular filtration. The aim of this study was to...

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Опубликовано в: :Braz J Med Biol Res
Главные авторы: Caires, A., Fernandes, G.S., Leme, A.M., Castino, B., Pessoa, E.A., Fernandes, S.M., Fonseca, C.D., Vattimo, M.F., Schor, N., Borges, F.T.
Формат: Artigo
Язык:Inglês
Опубликовано: Associação Brasileira de Divulgação Científica 2017
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731326/
https://ncbi.nlm.nih.gov/pubmed/29267497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20176373
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