Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats

Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased renal blood flow (RBF) and glomerular filtration. The aim of this study was to...

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Detalhes bibliográficos
Publicado no:Braz J Med Biol Res
Main Authors: Caires, A., Fernandes, G.S., Leme, A.M., Castino, B., Pessoa, E.A., Fernandes, S.M., Fonseca, C.D., Vattimo, M.F., Schor, N., Borges, F.T.
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731326/
https://ncbi.nlm.nih.gov/pubmed/29267497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20176373
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