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Antioxidant effect of endothelin-1 receptor antagonist protects the rat kidney against chronic injury induced by hypertension and hyperglycemia

Hypertension and Diabetes mellitus are the two main causes of chronic kidney disease that culminate in the final stage of kidney disease. Since these two risk factors are common and can overlap, new approaches to prevent or treat them are needed. Macitentan (MAC) is a new non-selective antagonist of...

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Detalhes bibliográficos
Publicado no:J Bras Nefrol
Main Authors: Caires, Agnaldo, Convento, Marcia Bastos, Castino, Bianca, Leme, Ala Moana, Pessoa, Edson de Andrade, Aragão, Alef, Schor, Nestor, Borges, Fernanda Teixeira
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Nefrologia 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979570/
https://ncbi.nlm.nih.gov/pubmed/31508666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/2175-8239-JBN-2018-0162
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