Antioxidant effect of endothelin-1 receptor antagonist protects the rat kidney against chronic injury induced by hypertension and hyperglycemia

Hypertension and Diabetes mellitus are the two main causes of chronic kidney disease that culminate in the final stage of kidney disease. Since these two risk factors are common and can overlap, new approaches to prevent or treat them are needed. Macitentan (MAC) is a new non-selective antagonist of...

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Podrobná bibliografie
Vydáno v:J Bras Nefrol
Hlavní autoři: Caires, Agnaldo, Convento, Marcia Bastos, Castino, Bianca, Leme, Ala Moana, Pessoa, Edson de Andrade, Aragão, Alef, Schor, Nestor, Borges, Fernanda Teixeira
Médium: Artigo
Jazyk:Inglês
Vydáno: Sociedade Brasileira de Nefrologia 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979570/
https://ncbi.nlm.nih.gov/pubmed/31508666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/2175-8239-JBN-2018-0162
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