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Experimental cyclosporin A nephrotoxicity.

The nephrotoxic property of cyclosporin A (Cy A) was investigated in groups of Sprague-Dawley rats given various dose regimes over a 21-day period. Impairment of glomerular filtration was clearly evidenced by elevated serum urea and creatinine levels and by reduced urea clearance rates. There were a...

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Detalhes bibliográficos
Main Authors: Whiting, P. H., Thomson, A. W., Blair, J. T., Simpson, J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040750/
https://ncbi.nlm.nih.gov/pubmed/7066186
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