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Experimental cyclosporin A nephrotoxicity.
The nephrotoxic property of cyclosporin A (Cy A) was investigated in groups of Sprague-Dawley rats given various dose regimes over a 21-day period. Impairment of glomerular filtration was clearly evidenced by elevated serum urea and creatinine levels and by reduced urea clearance rates. There were a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1982
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040750/ https://ncbi.nlm.nih.gov/pubmed/7066186 |
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