Pathological changes in rats receiving cyclosporin A at immunotherapeutic dosage for 7 weeks.

In rats given an immunotherapeutic dose (25 mg/kg orally each day for 7 weeks) of cyclosporin A (Cy A) characteristic drug-induced pathological changes were observed, including impaired liver function, renal proximal tubular cell damage, progressive lymphopenia, lymphocyte depletion in lymphoid orga...

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Bibliographic Details
Main Authors: Whiting, P. H., Simpson, J. G., Davidson, R. J., Thomson, A. W.
Format: Artigo
Language:Inglês
Published: 1983
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040790/
https://ncbi.nlm.nih.gov/pubmed/6615711
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