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Arginine feeding modifies cyclosporine nephrotoxicity in rats.

Glycine (G) infusion causes renal vasodilation mediated by nitric oxide (NO). Cyclosporine A (CsA) nephrotoxicity is characterized by preglomerular vasoconstriction and decreased efferent arteriolar tone probably related to reduced NO and angiotensin II, respectively. L-Arginine (ARG) is a precursor...

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Main Authors: De Nicola, L, Thomson, S C, Wead, L M, Brown, M R, Gabbai, F B
格式: Artigo
語言:Inglês
出版: 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC288350/
https://ncbi.nlm.nih.gov/pubmed/8408638
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