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A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions
Assessment of pharmacodynamic (PD) drug interactions is a cornerstone of the development of combination drug therapies. To guide this venture, we derive a general pharmacodynamic interaction (GPDI) model for ≥2 interacting drugs that is compatible with common additivity criteria. We propose a PD int...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5730559/ https://ncbi.nlm.nih.gov/pubmed/29242552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01929-y |
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