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Evaluation of optimized bronchoalveolar lavage sampling designs for characterization of pulmonary drug distribution
Bronchoalveolar lavage (BAL) is a pulmonary sampling technique for characterization of drug concentrations in epithelial lining fluid and alveolar cells. Two hypothetical drugs with different pulmonary distribution rates (fast and slow) were considered. An optimized BAL sampling design was generated...
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| Publicado no: | J Pharmacokinet Pharmacodyn |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624821/ https://ncbi.nlm.nih.gov/pubmed/26316105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9438-9 |
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