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Evaluation of optimized bronchoalveolar lavage sampling designs for characterization of pulmonary drug distribution
Bronchoalveolar lavage (BAL) is a pulmonary sampling technique for characterization of drug concentrations in epithelial lining fluid and alveolar cells. Two hypothetical drugs with different pulmonary distribution rates (fast and slow) were considered. An optimized BAL sampling design was generated...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Pharmacokinet Pharmacodyn |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer US
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624821/ https://ncbi.nlm.nih.gov/pubmed/26316105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9438-9 |
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