A model-informed preclinical approach for prediction of clinical pharmacodynamic interactions of anti-TB drug combinations

BACKGROUND: Identification of pharmacodynamic interactions is not reasonable to carry out in a clinical setting for many reasons. The aim of this work was to develop a model-informed preclinical approach for prediction of clinical pharmacodynamic drug interactions in order to inform early anti-TB dr...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Clewe, Oskar, Wicha, Sebastian G, de Vogel, Corné P, de Steenwinkel, Jurriaan E M, Simonsson, Ulrika S H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890720/
https://ncbi.nlm.nih.gov/pubmed/29136155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx380
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