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Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in prodromal Alzheimer’s disease

BACKGROUND: Beta-amyloid (Aβ) is the product of concerted cleavage of the amyloid precursor protein (APP) by β- and γ-secretases. However, the molecular mechanisms that regulate this process are not well understood. Recently evidence was reported that γ-secretase activating protein (GSAP, 16 kDa), d...

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Podrobná bibliografie
Vydáno v:Neurodegener Dis
Hlavní autoři: Perez, Sylvia E., Nadeem, Muhammad, Malek-Ahmadi, Michael H., He, Bin, Mufson, Elliott J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730491/
https://ncbi.nlm.nih.gov/pubmed/28743126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000477937
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