Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease

Hippocampal precursor of nerve growth factor (proNGF)/NGF signaling occurs in conjunction with β-amyloid (Aβ) accumulations in Alzheimer disease (AD). To assess the involvement of this pathway in AD progression, we quantified these proteins and their downstream pathway activators in postmortem tissu...

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Autors principals: Mufson, Elliott J., He, Bin, Nadeem, Muhammad, Perez, Sylvia E., Counts, Scott E., Leurgans, Sue, Fritz, Jason, Lah, James, Ginsberg, Stephen D., Wuu, Joanne, Scheff, Stephen W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481187/
https://ncbi.nlm.nih.gov/pubmed/23095849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318272caab
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